Feb 6, 2011 DICER1 knockdown induces accumulation of Alu RNA in human RPE cells and Alu-like B1 and B2 RNAs in mouse RPE. Retinal Pigment Epithelium/enzymology; Retinal Pigment Epithelium/metabolism; Retinal Pigment Epithelium/pathology; Ribonuclease III/deficiency*; Ribonuclease III/genetics .
nižší pigmentace oka
May 22, 2015 Here we describe that HAdV-37 infection leads to downregulation of CYP51A1 expression and overexpression of its antisense non-coding Alu element (AluCYP51A1) in retinal pigment epithelium (RPE) cells. This change in gene expression is associated with a reversed accumulation of a positive histone .
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Feb 24, 2011 Acucela's ACU-4429, a small molecule that targets the retinal pigment epithelium–specific protein 65 kDa (RPE65) to modulate the visual cycle, is in Phase II testing to treat dry AMD. Ambati thinks targeting Alu RNA might have advantages over the other strategies. “Compared with complement inhibitors, .
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Cutan Ocul Toxicol. 2018 Mar;37(1):52-60. doi: 10.1080/15569527.2017.1335748. Epub 2017 Jun 20. Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells. Chong YS(1), Mai CW(2), Leong CO(3), Wong LC(2). Author information: (1)a School.
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A lake pigment is a pigment manufactured by precipitating a dye with an inert binder, or "mordant", usually a metallic salt. Unlike vermilion, ultramarine, and other pigments made from ground minerals, lake pigments are organic. Manufacturers and suppliers to artists and industry frequently omit the lake designation in the .
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Nov 29, 2016 Fig. 4. Pyroptosis can dominate over apoptosis in retinal pigment epithelium (RPE) cells containing lipofuscin and irradiated with blue light, when these processes induce activation of the NLRP3 inflammasome. The Alu transposons are common in the human genome, and the amount of their transcripts.